Alpha is proud to partner and collaborate with Reproductive BioMedicine Online (RBMO) - a leading journal in clinical embryology and assisted reproduction. Paid Alpha membership provides free access to RBMO as the official journal of our society!
This page showcases selected papers from Volume 48 and other highlights from the journal.
RBMO Volume 48 Hot Topics
A compact, high-throughput semi-automated embryo vitrification system based on hydrogel
Shanshan Wang, Lei Chen, Junshun Fang, Haixiang Sun
RBMO Editors’ comments: Automation is the next frontier in the ART laboratory. This paper proposes an innovative way to achieve automated vitrification using hydrogel with proof-of-concept results that match manual processes.
Progesterone levels on the day of blastocyst transfer in modified natural cycle frozen embryo transfer cycles: a sub-study of an ongoing randomised controlled trial
M. Saupstad, S.J. Bergenheim, J.W. Bogstad, M.R. Petersen, A. Klajnbard, L. Prætorius, N.l.C. Freiesleben, A.L. Englund, E.C.L. Løkkegaard, U.B. Knudsen, M. Husth, B. Alsbjerg, J.E. Møller, T.V. Dam, J.L. Forman, A. Pinborg, K. Løssl
RBMO Editors’ comments: There is growing evidence for pregnancy complication benefits from frozen embryo transfer in a (modified) natural cycle. But is there a need to monitor and potentially supplement luteal progesterone levels? In data from a RCT, there was no relationship between progesterone level and achieving a clinical pregnancy or miscarriage in women who received no luteal support. However, this is very unlikely to be the final word on the subject.
Metabolic signature of follicular fluid to understand infertility-related diseases: a narrative review
Julie Fiscus, Éloïse Fraison, Lucie Renault, Bruno Salle, Baptiste Panthu, Elsa Labrune
RBMO Editors’ comments: For our February Hot Topics, we have selected two papers that highlight the impact of metabolic and immune changes on reproductive potential. Both the original research from Liu et al. and the Fiscus et al. narrative review illustrate the increasing interest we are seeing in this area, and we look forward to translation into clinically useful diagnostics or even therapies.
Initiation of ovarian stimulation independent of the menstrual cycle (random-start) in an oocyte donation programme: a large, single-center experience
Jaime Guerrero, Juan Carlos Castillo, Jorge Ten, JA Ortiz, Belén Lledó, Domingo Orozco, Francisco Quereda, Andrea Bernabeu, Rafael Bernabeu
RBMO Editors’ comments: Random start ovarian stimulation is increasingly widely used, since its origins as a way to minimise delays in fertility preservation. This analysis of its use in the context of oocyte donation supports its efficacy with no difference in LBR between follicular and luteal phase starts, as well as its convenience when there is no need to consider endometrial synchrony.
RBMO Insights
Monthly newsletter from RBMO, with Talking Points article features, journal updates, highlights, community news, event previews and more…
RBMO Digest
Quarterly collection of journal highlights selected by
Chief Editors Nick Macklon and Juan García-Velasco
Sustainability in the IVF Lab: an interview with Alpha Scientists and International IVF Initiative
Mina Alikani, Giles Palmer, Jacques Cohen, and Francesca Farlie from Alpha Scientists and the International IVF Initiative, lead authors and the organizing team behind recent paper ‘Sustainability in the IVF laboratory: recommendations of an expert panel’, sat down with RBMO for an interview to discuss the genesis of the project, the issues they are tackling and their recommendations for the future of green IVF.