Welcome to SCOPE ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
Alpha Scientists in Reproductive Medicine

Welcome to SCOPE

Welcome to the second edition of SCOPE. We are excited to continue this endeavour as we build on last quarter’s theme and look ahead together. SCOPE will continue to focus on a different topic each quarter, shedding light on the daily challenges, triumphs and unique experiences that fellow ART laboratory professionals understand well. 

We hope to bring the global embryology community together to stimulate thought-provoking discussions by sharing insights, tips and experiences.

A Quarter in review: key highlights & insights

In the last SCOPE edition, we asked if you had strategies for preventing straws or vials from sinking to the bottom of liquid nitrogen dewars - an unfortunate event that many embryologists have faced in their laboratory. The responses revealed a split in practice and concern: nearly half of participants reported that they cap their goblets in cryostorage, while 35% expressed strong interest in learning what other methods might exist to avoid this problem.

Discussions brought out techniques such as capping goblets and the use of cryosleeves to provide a short-term, low-cost fix, yet they do not address the underlying issue. That samples continue to end up where they should not be reflects a serious flaw in current cryostorage systems. Retrieving material from deep within a dewar is not only difficult and risky for the operator, it also risks compromising sample integrity.

Rather than relying on improvised solutions of emptying dewars and introducing claw-grabbing tools to retrieve these samples, we encourage you to consider more robust storage options that eliminate the problem of lost samples altogether. Investment in automation offers a path forward, where sample retrieval from the depths of a dewar becomes a thing of the past. With safety and precision at its core, automated cryostorage can redefine the protection and management of biological samples, reducing risk while increasing efficiency and trust.

📢SCOPE Focus of the Quarter: “Working It Out - Ergonomics in the IVF Lab”

When we think about safety and efficiency in the IVF laboratory, our first instinct is often to focus on the gametes and embryos that we handle. But what about the embryologists themselves? This quarter, we’re turning our attention to ergonomics - the science of designing environments and processes to fit the people who use them.

In the context of an IVF laboratory, ergonomics means more than just comfort. It’s about creating a workspace that minimises fatigue, reduces the risk of strain or injury, and ultimately supports precision, consistency, and wellbeing. A well-designed lab doesn’t just safeguard the embryologists; it also enhances the quality of care delivered to patients.

Over the coming weeks, we’ll explore this topic on several levels through a series of SCOPE polls, each addressing a different aspect of ergonomics.

🔍 What’s your take? 🗳️: How do you feel about ergonomics in your IVF laboratory? Is it a priority or an area where improvements could be made? Join the conversation and cast your vote as we explore this important topic and its potential impact on lab practices. 

Head over to  Alpha Scientists in Reproductive Medicine LinkedIn Page to take part.

Results and insights will be shared in the next SCOPE - don’t miss it!

Art of ARTists®

We continue to celebrate creativity and beauty in our field! We invite you to share your artistic vision - whether it’s a stunning illustration, a creative depiction of lab work, a photograph or a unique perspective on embryo development. This edition of SCOPE features a beautiful submission from Ireen Alland (USA), capturing the elegance of embryo development. Show us your art and inspire your colleagues - your work could be featured in the next issue!

 View the Art of ARTists here 

Ireen Alland, Embryologist, USA

💡Sustainability Spotlight

In every laboratory, expired media and unused consumables are an unfortunate reality. While strict regulations prevent their use in clinical practice, there are steps we can take to minimise waste and ensure these resources do not simply go to a landfill.

The first step toward that goal is prevention. More effective stock keeping and ordering can reduce the likelihood and risk of holding expired products in the first place. Work closely with suppliers to understand the expiry dates of incoming products, use technology and align orders with realistic consumption expectations. A proactive communication channel can help avoid unnecessary overstocking and waste.

When expiry does occur, consider alternative pathways. Universities and colleges offering courses in ART or laboratory practice are often underfunded and may welcome donations of expired media or consumables for training purposes. While these materials are unsuitable for clinical use, they can provide invaluable support for teaching environments, helping the next generation of embryologists gain hands-on experience.

By redirecting materials that would otherwise be discarded, we contribute to the circular economy, minimize laboratory waste, and invest in the future of our profession. Small steps like these promote sustainability and strengthen the wider community of reproductive scientists.

Keeping up With Literature

Keep at the forefront of Reproductive BioMedicine with the latest cutting-edge research!

Explore a curated selection of must-read articles from Reproductive BioMedicine Online (RBMO) that are driving the future of IVF.

Click here to see the RBMO journal on the ALPHA wesbite.

Want full access? As an ALPHA member, you get full-access to RBMO, bypassing the paywall to stay updated on the latest scientific advances - ensuring you’re always informed with high quality, up-to-date research. 

Not a member yet? Join ALPHA today, and unlock the science that drives progress in IVF! 

Thinking of Publishing in RBMO? If you are considering publishing your research in RBMO, we encourage you to watch the latest I3 webinar sponsored by RBMO “Session 160: Journal submission masterclass“. This session provides valuable insights into the submission process and offers practical tips on how to elevate a good paper into an excellent one.

 JOIN NOW! 

Consensus: Collective Insights, Shared Direction

One of ALPHA’s strengths has always been its ability to bring together leading voices in IVF and collaborate with other societies and groups to develop consensus papers. These documents educate practitioners on best practices and set standards that unite our field and guide future innovation.

We want to hear from you: What topic should ALPHA explore next to help harmonise and advance the practice of embryology worldwide?

Share your ideas on the ALPHA – Reproductive Scientists in Reproductive Medicine LinkedIn Page. Your input will help shape future conversations.

We are pleased to announce the scientific programme for the 15th Biennial ALPHA Conference 2026! The conference will take place at the Valamar Lacroma Hotel, Dubrovnik, Croatia, Friday 17 April – Sunday 19 April 2026.

We are delighted to invite you to explore this exciting and dynamic schedule, designed to advance knowledge, spark conversation and collaboration, and address the most critical and cutting-edge topics in our field.

Click here to view the programme

Become a Member and Save
Ready to save on your registration? Become a member to receive exclusive conference rates. Visit the website to learn more about membership fees.

Click here to register now!

Call for Papers
We invite scientists in reproductive medicine to submit their papers on the following categories:

  • Andrology

  • Cryopreservation

  • Embryology

  • Ethics and Law

  • Genetics

  • Psychology and Counselling

  • Safety and Quality

Papers will be considered as either ePosters or Short Paper presentations at the conference. The submission deadline is 23:59 on Monday 1 December 2025.

Submit your paper

On My Mind…

Closing message from the Executive Committee 

Keshav Malhotra, MBBS, M.ClinEmbryol, FICRM shares reflections on ALPHA’s contribution at the recent ACE meeting.


ALPHA at ACE 2025

Bhubaneswar’s halls were alive with the kind of hum that only embryologists create - quiet focus at the benches in the morning, animated debate by afternoon, and calm conversation by evening. ALPHA was represented by Alison Campbell, Mina Alikani, Dean Morbeck, and Keshav Malhotra, and together the team shaped an exchange that was equal parts science, craft, and community.

Mina opened with the question that matters most: Why do outcomes vary across laboratories, and what can we do about it? She walked the audience through practical levers that shrink variance. The message landed clearly. When we standardize, we improve.

Consensus as a compass

ALPHA Session
Istanbul Consensus 2025 — 20 key recommendations
Speaker: Alison Campbell
Alison presented the updated Istanbul consensus on oocyte and embryo assessment. The emphasis was on evidence and usable guidance and the collective effort that is required to reduce embryo assessment subjectivity.
Click here to read the updated Istanbul consensus on oocyte and embryo assessment.


Supporting the next generation of embryologists

Essentials of Embryology: What every trainee should be taught
Speaker: Alison Campbell
This session felt like a blueprint for training. Alison covered some overlooked examples of essential embryology teaching. She spoke about liquid nitrogen safety, the importance of precise, fast dish preparation, centrifuge speed, documentation and data. The takeaway was simple: competency is a continuum. It is formed under supervision, measured against clear milestones, and refreshed over a career.

Embryo Ranking in Practice: Challenges, consensus, and clinical decision-making
Panelists: Alison Campbell, Keshav Malhotra
A grounded conversation on what happens when the rubric meets the real patient. Day 5 vs day 6, ICM vs TE when features conflict, how AI-assisted signals are weighed against clinical nuance, and how to speak about uncertainty without eroding confidence.  

In the workshops, ideas met the bench. “Beyond the Basics,” led by Alison Campbell, dove into case-based troubleshooting, the small fixes that prevent big errors, and pattern-recognition across recurring issues. “Quality Control,” convened by Keshav Malhotra, turned policy into practice with incident reporting people actually use, near-miss learning.Dean Morbeck’s virtual lecture unpacked osmolality across culture stages with crisp guidance on measurement, drift, and downstream impact.

 

Global Voices

Video presentation curated by ALPHA, introduced by Alison Campbell
This got a primetime slot at the conference and was played just before the inauguration ceremony. Short snippets from different regions showed ingenuity under constraint and reminded everyone why exchange matters.


Partnership in action

ACE will participate in an exchange session at the ALPHA Congress next year, ensuring that this collaboration deepens.

 

Gratitude and next steps

Our thanks to the ACE scientific committee and Sujatha, Gaurav and Phalguni for curating a program that was rigorous yet so warm. The conversations in Bhubaneswar did more than filling an agenda. They sharpened the tools we use, clarified the words we share, and reaffirmed the values we stand on.

Join ALPHA through the ACE member offer, share these sessions with your teams, and bring one new quality habit into your lab this month. Small steps, consistently taken, change outcomes.

Alpha Scientists in Reproductive Medicine

Alpha Scientists in Reproductive Medicine, Suite 213 Boundary House, Boston Road, London, W7 2QE

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